Treadmill workout activates PPARα in the hippocampus to upregulate ADAM10, decrease plaques and improve cognitive functions in 5XFAD mouse model of Alzheimer’s disease
Author:
Funder
National Institutes of Health
U.S. Department of Veterans Affairs
Publisher
Elsevier BV
Subject
Behavioral Neuroscience,Endocrine and Autonomic Systems,Immunology
Reference65 articles.
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1. ADAM10 isoforms: Optimizing usage of antibodies based on protein regulation, structural features, biological activity and clinical relevance to Alzheimer’s disease;Ageing Research Reviews;2024-11
2. Activation of the muscle-to-brain axis ameliorates neurocognitive deficits in an Alzheimer’s disease mouse model via enhancing neurotrophic and synaptic signaling;GeroScience;2024-09-13
3. Identification of Cinnamein, a Component of Balsam of Tolu/Peru, as a New Ligand of PPARα for Plaque Reduction and Memory Protection in a Mouse Model of Alzheimer’s Disease;Journal of Alzheimer's Disease Reports;2024-05-24
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