Inhibition of HBV replication by N-hydroxyisoquinolinedione and N-hydroxypyridinedione ribonuclease H inhibitors-Reference-Cited by-同舟云学术

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Inhibition of HBV replication by N-hydroxyisoquinolinedione and N-hydroxypyridinedione ribonuclease H inhibitors

Published:2019-04 Issue: Volume:164 Page:70-80
ISSN:0166-3542
Container-title:Antiviral Research
language:en
Short-container-title:Antiviral Research

Author:

Edwards Tiffany C.,Mani Nagraj^ORCID,Dorsey Bruce^ORCID,Kakarla Ramesh,Rijnbrand Rene,Sofia Michael J.,Tavis John E.

Funder

Arbutus Biopharma

NIH

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference27 articles.

1. Hepatitis B virus replication is blocked by a 2-hydroxyisoquinoline-1,3(2H,4H)-dione (HID) inhibitor of the viral ribonuclease H activity;Cai;Antivir. Res.,2014

2. Establishment of an inducible HBV stable cell line that expresses cccDNA-dependent epitope-tagged HBeAg for screening of cccDNA modulators;Cai;Antivir. Res.,2016

3. Drug combination studies and their synergy quantification using the Chou-Talalay method;Chou;Cancer Res.,2010

4. Molecular characterization of intrahepatic and extrahepatic hepatitis B virus (HBV) reservoirs in patients on suppressive antiviral therapy;Coffin;J. Viral Hepat.,2011

5. Emerging pipeline drugs for hepatitis B infection;Cox;Expert Opin. Emerg. Drugs,2011

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1. Novel mechanistic insights – A brand new Era for anti-HBV drugs;European Journal of Medicinal Chemistry;2024-12

2. N-Hydroxypiridinedione: A Privileged Heterocycle for Targeting the HBV RNase H;Molecules;2024-06-20

3. Identification and assessment of the 1,6-dihydroxy-pyridin-2-one moiety as privileged scaffold for HBV ribonuclease H inhibition;Antiviral Research;2024-03

4. In Vitro Enzymatic and Cell Culture-Based Assays for Measuring Activity of HBV Ribonuclease H Inhibitors;Methods in Molecular Biology;2024

5. Conditional replication and secretion of hepatitis B virus genome uncover the truncated 3′ terminus of encapsidated viral pregenomic RNA;Journal of Virology;2023-10-31

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