Hepatitis B virus replication is blocked by a 2-hydroxyisoquinoline-1,3(2H,4H)-dione (HID) inhibitor of the viral ribonuclease H activity-Reference-Cited by-同舟云学术

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Hepatitis B virus replication is blocked by a 2-hydroxyisoquinoline-1,3(2H,4H)-dione (HID) inhibitor of the viral ribonuclease H activity

Published:2014-08 Issue: Volume:108 Page:48-55
ISSN:0166-3542
Container-title:Antiviral Research
language:en
Short-container-title:Antiviral Research

Author:

Cai Catherine W.,Lomonosova Elena,Moran Eileen A.,Cheng Xiaohong,Patel Kunjan B.,Bailly Fabrice,Cotelle Philippe,Meyers Marvin J.,Tavis John E.

Funder

Saint Louis University seed funds

NCATS

ANRS

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference34 articles.

1. Design, synthesis, and biological evaluation of a series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as dual inhibitors of human immunodeficiency virus type 1 integrase and the reverse transcriptase RNase H domain;Billamboz;J. Med. Chem.,2008

2. 2-hydroxyisoquinoline-1,3(2H,4H)-diones as inhibitors of HIV-1 integrase and reverse transcriptase RNase H domain: influence of the alkylation of position 4;Billamboz;Eur. J. Med. Chem.,2011

3. Magnesium chelating 2-hydroxyisoquinoline-1,3(2H,4H)-diones, as inhibitors of HIV-1 integrase and/or the HIV-1 reverse transcriptase ribonuclease H domain: discovery of a novel selective inhibitor of the ribonuclease H function;Billamboz;J. Med. Chem.,2011

4. 4-Substituted 2-hydroxyisoquinoline-1,3(2H,4H)-diones, as a novel class of HIV-1 integrase inhibitors;Billamboz;ACS. Med. Chem. Lett.,2013

5. Chronic hepatitis B: what should be the goal for new therapies?;Block;Antiviral Res.,2013

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1. N-Hydroxypiridinedione: A Privileged Heterocycle for Targeting the HBV RNase H;Molecules;2024-06-20

2. Identification and assessment of the 1,6-dihydroxy-pyridin-2-one moiety as privileged scaffold for HBV ribonuclease H inhibition;Antiviral Research;2024-03

3. In Vitro Enzymatic and Cell Culture-Based Assays for Measuring Activity of HBV Ribonuclease H Inhibitors;Methods in Molecular Biology;2024

4. Synthesis of nitro‐containing isoquinoline‐1,3‐diones with tert‐butyl nitrite;Journal of Heterocyclic Chemistry;2023-12-03

5. Advancing beyond reverse transcriptase inhibitors: The new era of hepatitis B polymerase inhibitors;European Journal of Medicinal Chemistry;2023-09

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