Glycyrrhizic acid conjugates with amino acid methyl esters target the main protease, exhibiting antiviral activity against wild-type and nirmatrelvir-resistant SARS-CoV-2 variants

Author:

Le Uyen Nguyen Phuong,Chang Yu-JenORCID,Lu Chih-HaoORCID,Chen Yeh,Su Wen-Chi,Chao Shao-Ting,Baltina Lia A.,Petrova Svetlana F.,Li Sin-Rong,Hung Mien-Chie,Lai Michael M.C.,Baltina Lidia A.ORCID,Lin Cheng-Wen

Publisher

Elsevier BV

Reference31 articles.

1. Antiviral activity of glycyrrhizic acid conjugates with amino acid esters against Zika virus;Baltina;Virus Res.,2021

2. Glycyrrhizic acid derivatives as Dengue virus inhibitors;Baltina;Bioorg. Med. Chem. Lett,2019

3. Combining virtual screening with cis-/trans-cleavage enzymatic assays effectively reveals broad-spectrum inhibitors that target the main proteases of SARS-CoV-2 and MERS-CoV;Chang;Antivir. Res.,2023

4. Resistance to nirmatrelvir due to mutations in the Mpro in the subvariants of SARS-CoV-2 Omicron: Another concern?;Chatterjee;Mol. Ther. Nucleic Acids,2023

5. SARS-CoV-2 Variant Mutations Conferring Reduced Susceptibility to Antiviral Drugs and Monoclonal Antibodies: a Non-systematic Literature Review for Surveillance Purposes – July 2023,2023

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