PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells

Author:

Calvo M.N.,Bartrons R.,Castaño E.,Perales J.C.,Navarro-Sabaté A.,Manzano A.

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Reference45 articles.

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2. Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia;Xu;Cancer Res.,2005

3. Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes;Altenberg;Genomics,2004

4. An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect;Chesney;Proc. Natl. Acad. Sci. USA,1999

5. Acquired glucose sensitivity of k-ras transformed fibroblasts;Chiaradonna;Biochem. Soc. Trans.,2005

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