Small-Molecule Inhibitors Targeting DNA Repair and DNA Repair Deficiency in Research and Cancer Therapy
Author:
Funder
NIH
University of Iowa
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry
Reference147 articles.
1. Targeting an Achilles' heel of cancer with a WRN helicase inhibitor;Aggarwal;Cell Cycle,2013
2. Werner syndrome helicase has a critical role in DNA damage responses in the absence of a functional Fanconi anemia pathway;Aggarwal;Cancer Res.,2013
3. Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress;Aggarwal;Proc. Natl. Acad. Sci. USA,2011
4. A small-molecule inhibitor of RAD51 reduces homologous recombination and sensitizes multiple myeloma cells to doxorubicin;Alagpulinsa;Front. Oncol.,2014
5. Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites;Altmeyer;Nucleic Acids Res.,2009
Cited by 112 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. The DNA damage-independent ATM signalling maintains CBP/DOT1L axis in MLL rearranged acute myeloid leukaemia;Oncogene;2024-04-26
2. A deep-learning-based genomic status estimating framework for homologous recombination deficiency detection from low-pass whole genome sequencing;Heliyon;2024-02
3. Improving homology‐directed repair by small molecule agents for genetic engineering in unconventional yeast?—Learning from the engineering of mammalian systems;Microbial Biotechnology;2024-02
4. Rhodanine derived enethiols react to give 1,3-dithiolanes and mixed disulfides;RSC Medicinal Chemistry;2024
5. DNA nicks in both leading and lagging strand templates can trigger break-induced replication;2023-12-22
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3