A mild and efficient route to the pharmacophore of the enediyne antitumor agents - (Z)-1,6-[bis (trimethylsilyl)-hex-3-ene-1,5-diyne via a novel carbenoid coupling reaction-Reference-Cited by-同舟云学术

A mild and efficient route to the pharmacophore of the enediyne antitumor agents - (Z)-1,6-[bis (trimethylsilyl)-hex-3-ene-1,5-diyne via a novel carbenoid coupling reaction

Published:1994-04 Issue:17 Volume:35 Page:2655-2658
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Huber Robert S.,Jones Graham B.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference8 articles.

1. Chemistry and Biology of the Enediyne Anticancer Antibiotics

2. Total synthesis of calicheamicinone: new arrangements for actuation of the reductive cycloaromatization of aglycon congeners

3. Synthesis and Chemistry of Enediyne Templates;Jones;45th South Eastern Regional ACS Meeting, Johnson City, TN,1993

4. Synthesis and DNA Cleaving Capacity of Novel Enediynes;Jones;45th South Eastern Regional ACS Meeting, Johnson City, TN,1993

5. Stereospecific syntheses fo cis- and trans-1,6-bistrimethylsilyl-hex-3-ene-1,5-diyne

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