Chemistry of FK-506: Benzilic acid rearrangement of the tricarbonyl system
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference14 articles.
1. A diastereospecific, non-racemic synthesis of the C.10–C.18 segment of FK-506
2. Diastereospecific, non-racemic synthesis of the C.20–C.34 segment of the novel immunosuppressant FK-506
3. A highly selective method for the synthesis of(E)-α-methyl-α,β-unsaturated aldehydes
4. Alkylation of chiral prolinol propionamide enolates with epoxides: Complete reversal of predicted facial selectivity
5. Structure of FK506, a novel immunosuppressant isolated from Streptomyces
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1. Natural Product Synthesis Enabled by Domino Processes Incorporating a 1,2-Rearrangement Step;ACS Central Science;2021-04-08
2. Catalytic Enantioselective Benzilic Ester Rearrangement;Angewandte Chemie International Edition;2020-03-09
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4. Aza-Riley Oxidation of Ugi-Azide and Ugi-3CR Products toward Vicinal Tricarbonyl Amides: Two-Step MCR-Oxidation Methodology Accessing Functionalized α,β-Diketoamides and α,β-Diketotetrazoles;Organic Letters;2018-02-21
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