Asymmetric synthesis of α,α-diaryl and α-aryl-α-heteroaryl alkylamines by organometallic additions to N-tert- butanesulfinyl ketimines

Author:

Shaw Anthony W,deSolms S.Jane

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference8 articles.

1. Diaryl ether inhibitors of farnesyl-protein transferase

2. deSolms, S. J.; Ciccarone, T. M.; MacTough, S. C.; Shaw, A. W.; Abrams, M. T.; Buser-Doepner, C.; Davide, J. P.; Hamiliton, K. A.; Huber, H. E.; Kohl, N. E.; Lobell, R. B.; Robinson, R. G.; Tsou, N. N.; Graham, S. L.; Beese, L. S.; Taylor, J. S.; manuscript in preparation.

3. Asymmetric synthesis of amino acids using sulfinimines (thiooxime S-oxides)

4. Asymmetric synthesis of chiral amines by highly diastereoselective 1,2-additions of organometallic reagents to N-tert-butanesulfinyl imines

5. Asymmetric Synthesis of α,α-Dibranched Amines by the Trimethylaluminum-Mediated 1,2-Addition of Organolithiums to tert-Butanesulfinyl Ketimines

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