Digital Twins in Pilot Scale Fermentation: Non-Linear State Estimation for Improving Induction Timing

Author:

Stevnsborg Mads,Selle Kurt,Barton Ryan,Prado-Rubio Oscar A.,Gargalo Carina,Gernaey Krist V.,Gilleskie Gary,Huusom Jakob K.

Publisher

Elsevier

Reference7 articles.

1. Challenges in Optimization and Control of Biobased Process Systems: An Industrial-Academic Perspective;Bähner;Industrial and Engineering Chemistry Research,2021

2. Towards Digitalization in Bio-Manufacturing Operations: A Survey on Application of Big Data and Digital Twin Concepts in Denmark: Frontiers;Udugama;Chemical Engineering,2021

3. Digital Twin of a pilot-scale bio-production setup;Muldbak;Computer Aided Chemical Engineering,2022

4. An experimental assessment of robust control and estimation of acetate concentration in Escherichia coli BL21(DE3) fed-batch cultures;Abadil;Biochemical Engineering Journal,2021

5. Improving the cost effectiveness of enhanced green fluorescent protein production using recombinant Escherichia coli BL21 (DE3): Decreasing the expression inducer concentration;Lopes;Biotechnology and Applied Biochemistry,2019

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