MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition-Reference-Cited by-同舟云学术

MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition

Published:2017-02 Issue:2 Volume:31 Page:270-285
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Mollaoglu Gurkan,Guthrie Matthew R.,Böhm Stefanie,Brägelmann Johannes,Can Ismail,Ballieu Paul M.,Marx Annika,George Julie,Heinen Christine,Chalishazar Milind D.,Cheng Haixia,Ireland Abbie S.,Denning Kendall E.,Mukhopadhyay Anandaroop,Vahrenkamp Jeffery M.,Berrett Kristofer C.,Mosbruger Timothy L.,Wang Jun,Kohan Jessica L.,Salama Mohamed E.,Witt Benjamin L.,Peifer Martin,Thomas Roman K.,Gertz Jason,Johnson Jane E.,Gazdar Adi F.,Wechsler-Reya Robert J.,Sos Martin L.,Oliver Trudy G.

Funder

V Foundation for Cancer Research

American Cancer Society

NIH

Damon Runyon Cancer Research Foundation

Köln Fortune Research Scholar Award

CPRIT

EFRE

German Ministry of Science and Education

Deutsche Forschungsgemeinschaft

Novartis

Deutsche Krebshilfe

CURELUNG

PerMed.NRW

American Association of Cancer Research Innovative Research Grant

German Consortium for Translational Cancer Research Joint Funding

AstraZeneca

EOS

Merck KgaA

Bayer

NEO New Oncology AG

Boehringer Ingelheim

Clovis Oncology

Daiichi-Sankyo

Eli Lilly

Johnson & Johnson

MSD

Puma

Roche

Sanofi

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference52 articles.

1. ASCL1 and NEUROD1 reveal heterogeneity in pulmonary neuroendocrine tumors and regulate distinct genetic programs;Borromeo;Cell Rep.,2016

2. myc family DNA amplification in 107 tumors and tumor cell lines from patients with small cell lung cancer treated with different combination chemotherapy regimens;Brennan;Cancer Res.,1991

3. Small molecule inhibitors of Aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma;Brockmann;Cancer Cell,2013

4. Small cell lung cancer: can recent advances in biology and molecular biology be translated into improved outcomes?;Bunn;J. Thorac. Oncol.,2016

5. A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer;Calbo;Cancer Cell,2011

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