Codon Modification and PAMPs in Clinical AAV Vectors: The Tortoise or the Hare?
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine
Reference15 articles.
1. Signaling in innate immunity and inflammation;Newton;Cold Spring Harb. Perspect. Biol.,2012
2. CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells;Hartmann;Proc. Natl. Acad. Sci. USA,1999
3. Toll-like receptor 9 contains two DNA binding sites that function cooperatively to promote receptor dimerization and activation;Ohto;Immunity,2018
4. The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice;Zhu;J. Clin. Invest.,2009
5. Type I IFN Sensing by cDCs and CD4+ T Cell Help Are Both Requisite for Cross-Priming of AAV Capsid-Specific CD8+ T Cells;Shirley;Mol. Ther,2019
Cited by 54 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Meeting Report: 2023 Muscular Dystrophy Association Summit on ‘Safety and Challenges in Gene Therapy of Neuromuscular Diseases’;Journal of Neuromuscular Diseases;2024-09-03
2. Correlation of antigen expression with epigenetic modifications after rAAV delivery of a human factor IX variant in mice and rhesus macaques;Molecular Therapy;2024-07
3. Innate Immune Sensing of Adeno-Associated Virus Vectors;Human Gene Therapy;2024-07-01
4. Adeno-associated virus vector-based gene therapy for hereditary diseases: current problems of application and approaches to solve them;Biological Products. Prevention, Diagnosis, Treatment;2024-06-20
5. AAV9-Mediated Intrastriatal Delivery ofGNAO1Reduces Hyperlocomotion inGnao1Heterozygous R209H Mutant Mice;Journal of Pharmacology and Experimental Therapeutics;2024-06-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3