Identification of factors that contribute to recombinant AAV2 particle aggregation and methods to prevent its occurrence during vector purification and formulation

Author:

Wright J. Fraser,Le Tannie,Prado Joseph,Bahr-Davidson Jennifer,Smith Peter H.,Zhen Zhu,Sommer Jurg M.,Pierce Glenn F.,Qu Guang

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference25 articles.

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2. AAV-mediated gene transfer for hemophilia;High;Ann. N.Y. Acad. Sci.,2001

3. Gene therapy: promises and problems;Pfeifer;Ann. Rev. Genomics Hum. Genet.,2001

4. Parvoviridae: the viruses and their replication;Berns,1996

5. The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy;Xie;Proc. Natl. Acad. Sci. USA,2002

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