Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach-Reference-Cited by-同舟云学术

Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach

Published:2001-10 Issue:20 Volume:11 Page:2775-2778
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Smith Roger A,Barbosa James,Blum Cheri L,Bobko Mark A,Caringal Yolanda V,Dally Robert,Johnson Jeffrey S,Katz Michael E,Kennure Nancy,Kingery-Wood Jill,Lee Wendy,Lowinger Timothy B,Lyons John,Marsh Vivienne,Rogers Daniel H,Swartz Stephen,Walling Tracy,Wild Hanno

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference14 articles.

1. FUNCTION AND REGULATION OF RAS

2. The Role of Raf Kinases in Development and Growth of Tumors

3. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase

4. The discovery of potent cRaf1 kinase inhibitors

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