Substituted acrylamides as factor Xa inhibitors: improving bioavailability by P1 modification

Author:

Song Yonghong,Clizbe Lane,Bhakta Chhaya,Teng Willy,Li Wenhao,Wong Paul,Huang Brian,Sinha Uma,Park Gary,Reed Andrea,Scarborough Robert M,Zhu Bing-Yan

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference12 articles.

1. Song, Y.; Clizbe, L.; Bhakta, C.; Teng, W.; Li, W.; Wu, Y.; Jia, Z. J.; Zhang, P.; Wang, L.; Doughan, B.; Su, T.; Kanter, J.; Woolfrey, J.; Wong, P.; Huang, B.; Tran, K.; Sinha, U.; Park, G.; Reed, A.; Malinowski, J.; Hollenbach, S.; Scarborough, R. M.; Zhu, B.-Y. Books of Abstracts, 221th National Meeting of the American Chemical Society, San Diego, CA, 1–5 April, 2001; American Chemical Society: Washington, DC, 2001; MEDI 063.

2. Chapter 9. Factor Xa inhibitors: Recent advances in anticoagulant agents

3. Chapter 8. Anticoagulants: Inhibitors of thrombin and factor Xa

4. Song, Y.; Clizbe, L.; Bhakta, C.; Teng, W.; Li, W.; Wu, Y.; Jia, Z. J.; Zhang, P.; Wang, L.; Doughan, B.; Su, T.; Kanter, J.; Woolfrey, J.; Wong, P.; Huang, B.; Tran, K.; Sinha, U.; Park, G.; Reed, A.; Malinowski, J.; Hollenbach, S.; Scarborough, R. M.; Zhu, B.-Y. Bioorg. Med. Chem. Lett. 2002, 12, 1511.

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