Evidence of enhanced type 2 immune response and impaired upregulation of a type 1 response in frail elderly nursing home residents

Author:

Castle Steven,Uyemura Koichi,Wong Wendy,Modlin Robert,Effros Rita

Publisher

Elsevier BV

Subject

Developmental Biology,Aging

Reference16 articles.

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3. M. Kubin, J.M. Chow and G. Trinchieri, Differential regulation of interleukin-12 (IL-12), tumor necrosis factor alpha, and IL-1 beta production in human myeloid leukemia cell lines and peripheral blood mononuclear cells. Blood, 83 (1994) 1847.

4. M.K. Gately, B.B. Desai, A.G. Wolitsky et al., Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor). J. Immunol., 147 (1991) 874.

5. D.F. Fiorentino, M.W. Bond and T.R. Mosmann, Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med., 170 (1989) 2081.

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