Small-molecule modulators of PXR and CAR-Reference-Cited by-同舟云学术

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Small-molecule modulators of PXR and CAR

Published:2016-09 Issue:9 Volume:1859 Page:1141-1154
ISSN:1874-9399
Container-title:Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Author:

Chai Sergio C.,Cherian Milu T.,Wang Yue-Ming,Chen Taosheng

Funder

St. Jude Children's Research Hospital

National Institutes of Health

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Reference158 articles.

1. PXR, CAR and drug metabolism;Willson;Nat. Rev. Drug Discov.,2002

2. Role of CAR and PXR in xenobiotic sensing and metabolism;Wang;Expert Opin. Drug Metab. Toxicol.,2012

3. Xenobiotic metabolomics: major impact on the metabolome;Johnson;Annu. Rev. Pharmacol.,2012

4. Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR;Tolson;Adv. Drug Deliv. Rev.,2010

5. Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1;Wang;Toxicol. Appl. Pharmacol.,2013

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