Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity-Reference-Cited by-同舟云学术

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Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity

Published:2016-09 Issue:9 Volume:1859 Page:1155-1169
ISSN:1874-9399
Container-title:Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Author:

Pasquel Danielle,Doricakova Aneta,Li Hao,Kortagere Sandhya,Krasowski Matthew D.,Biswas Arunima,Walton William G.,Redinbo Matthew R.,Dvorak Zdenek,Mani Sridhar

Funder

National Institutes of Health

Damon Runyon Foundation Clinical Investigator Award

Czech Science Agency

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Reference119 articles.

1. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism;Kliewer;Endocr. Rev.,2002

2. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway;Kliewer;Cell,1998

3. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions;Lehmann;J. Clin. Invest.,1998

4. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids;Xie;Proc. Natl. Acad. Sci. U. S. A.,2001

5. PXR cross-talks with internal and external signals in physiological and pathophysiological responses;Kodama;Drug Metab. Rev.,2013

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1. Dose‐dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin;Clinical and Translational Science;2024-08

2. Regulation of PXR in drug metabolism: chemical and structural perspectives;Expert Opinion on Drug Metabolism & Toxicology;2024-01-28

3. S-nitrosylation attenuates pregnane X receptor hyperactivity and acetaminophen-induced liver injury;JCI Insight;2024-01-23

4. Dual Role of Pregnane X Receptor in Nonalcoholic Fatty Liver Disease;Current Molecular Pharmacology;2023-11-17

5. ncBAF enhances PXR-mediated transcriptional activation in the human and mouse liver;Biochemical Pharmacology;2023-09

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