Synthesis, antiangiogenesis evaluation and molecular docking studies of 1-aryl-3-[(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas: Discovery of a new substitution pattern for type II VEGFR-2 Tyr kinase inhibitors-Reference-Cited by-同舟云学术

Synthesis, antiangiogenesis evaluation and molecular docking studies of 1-aryl-3-[(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas: Discovery of a new substitution pattern for type II VEGFR-2 Tyr kinase inhibitors

Published:2015-10 Issue:19 Volume:23 Page:6497-6509
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Machado Vera A.,Peixoto Daniela,Costa Raquel,Froufe Hugo J.C.,Calhelha Ricardo C.,Abreu Rui M.V.,Ferreira Isabel C.F.R.,Soares Raquel,Queiroz Maria-João R.P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference28 articles.

1. A review of the latest clinical compounds to inhibit VEGF in pathological angiogenesis

2. Molecular mechanisms and clinical applications of angiogenesis

3. Rational design of inhibitors that bind to inactive kinase conformations

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