Identification of selective inhibitors of sphingosine kinases 1 and 2 through a structure–activity relationship study of 4- epi -jaspine B-Reference-Cited by-同舟云学术

Identification of selective inhibitors of sphingosine kinases 1 and 2 through a structure–activity relationship study of 4- epi -jaspine B

Published:2017-06 Issue:12 Volume:25 Page:3046-3052
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Ohno Hiroaki,Honda Maho,Hamada Naoka,Miyagaki Jun,Iwata Akira,Otsuki Kazuhiro,Maruyama Toru,Nakamura Shinya,Nakanishi Isao,Inuki Shinsuke,Fujii Nobutaka,Oishi Shinya

Funder

JSPS

Uehara Memorial Foundation

Ministry of Education

MEXT

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference52 articles.

1. Importance of Sphingosine Kinase (SphK) as a Target in Developing Cancer Therapeutics and Recent Developments in the Synthesis of Novel SphK Inhibitors

2. Drugging Sphingosine Kinases

3. Recent advances in the development of sphingosine kinase inhibitors

4. Sphingosine Kinase 2 Is a Nuclear Protein and Inhibits DNA Synthesis

5. Therapeutic Potential of Targeting SK1 in Human Cancers

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