The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-Reference-Cited by-同舟云学术

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The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase

Published:2014-04 Issue:7 Volume:22 Page:2157-2165
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Yun Mi-Kyung,Hoagland Daniel^ORCID,Kumar Gyanendra,Waddell M. Brett,Rock Charles O.,Lee Richard E.,White Stephen W.

Funder

National Institutes of Health

Cancer Center (CORE)

American Lebanese Syrian Associated Charities (ALSAC)

Michigan State University

U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference40 articles.

1. The folic acid biosynthesis pathway in bacteria: evaluation of potential for antibacterial drug discovery

2. Crystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensis

3. The structure and function of the 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Haemophilus influenzae 1 1Edited by R. Huber

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1. Crystal structure of Arabidopsis thaliana HPPK/DHPS, a bifunctional enzyme and target of the herbicide asulam;Plant Communications;2022-07

2. Crystal structure of Arabidopsis thaliana HPPK/DHPS, a bifunctional enzyme and target of the herbicide asulam;2021-11-12

3. Virtual screening and in vitro validation identifies the first reported inhibitors of Salmonella enterica HPPK;RSC Medicinal Chemistry;2021

4. Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Transition state analogs for high affinity binding;Bioorganic & Medicinal Chemistry;2021-01

5. Structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase–dihydropteroate synthase from Plasmodium vivax sheds light on drug resistance;Journal of Biological Chemistry;2018-09

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