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Fluorinated 2-Arylcyclopropan-1-amines – A new class of sigma receptor ligands

  • Published:2020-11 Issue:22 Volume:28 Page:115726
  • ISSN:0968-0896
  • Container-title:Bioorganic & Medicinal Chemistry
  • language:en
  • Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Schinor Benjamin,Hruschka Svenja,Daniliuc Constantin G.,Schepmann Dirk,Wünsch Bernhard,Haufe Günter

Funder

Deutsche Forschungsgemeinschaft

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference59 articles.

1. The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog;Martin;J Pharmacol Exp Ther,1976

2. Naltrexone fails to antagonize the σ-effects of PCP and SKF 10,047 in the dog;Vaupel;Eur J Pharmacol,1983

3. Sigma Receptors: Historical Perspective and Background;Matsumoto,2007

4. A sigma-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from that of guinea pig brain;Hellewell;Brain Res,1990

5. Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling;Hellewell;Eur J Pharmacol,1994

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