Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors-Reference-Cited by-同舟云学术

Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors

Published:2006-10 Issue:20 Volume:14 Page:6832-6846
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Woods Keith W.,Fischer John P.,Claiborne Akiyo,Li Tongmei,Thomas Sheela A.,Zhu Gui-Dong,Diebold Robert B.,Liu Xuesong,Shi Yan,Klinghofer Vered,Han Edward K.,Guan Ran,Magnone Shayna R.,Johnson Eric F.,Bouska Jennifer J.,Olson Amanda M.,Jong Ron de,Oltersdorf Tilman,Luo Yan,Rosenberg Saul H.,Giranda Vincent L.,Li Qun

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. Targeting Serine / Threonine Protein Kinase B / Akt and Cell-cycle Checkpoint Kinases for Treating Cancer

2. Emerging targets in the AKT pathway for treatment of androgen-independent prostatic adenocarcinoma

3. The protein kinase B/Akt signalling pathway in human malignancy

4. The phosphatidylinositol 3-Kinase–AKT pathway in human cancer

5. Targeting the PI3K-Akt pathway in human cancer

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