Metabolomic-based investigation of Yinlan alleviating hyperlipidemia by inhibiting blood stasis and phlegm turbidity through the PXR-CYP3A4-ABCB1-FXR pathway

Author:

Li Dongmei,Xiao Guanlin,Chen Weitao,Zeng Xiaohui,Cao Li-Zhong,Chen Zhao

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

General Chemical Engineering,General Chemistry

Reference43 articles.

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2. Bile acid activated receptors: Integrating immune and metabolic regulation in non-alcoholic fatty liver disease;Biagioli;Liver Res.,2021

3. Novel pathways of bile acid metabolism involving CYP3A4;Bodin;Biochim. Biophys. Acta (BBA) - Mol. Cell Biol. Lipids,2005

4. Nuclear receptor FXR, bile acids and liver damage: Introducing the progressive familial intrahepatic cholestasis with FXR mutations;Cariello;BBA – Mol. Basis Dis.,2018

5. Selection and evaluation of quality markers from Yinlan capsule and its LXRα-mediated therapy for hyperlipidemia;Chen;Phytomed.,2019

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