Aucubin provides protection against cerebral ischaemia-reperfusion injury by suppressing neuronal apoptosis, oxidative stress, and inflammation through the modulation of the AKT-GSK-3β-Nrf2 signal cascade-Reference-Cited by-同舟云学术

Aucubin provides protection against cerebral ischaemia-reperfusion injury by suppressing neuronal apoptosis, oxidative stress, and inflammation through the modulation of the AKT-GSK-3β-Nrf2 signal cascade

Published:2024-02 Issue: Volume:483 Page:116829
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Yang Fang,Lian Qiufang,Zhang Xin,Sun Feng,Jia Shuaiyun,Zhao Wei

Publisher

Elsevier BV

Reference32 articles.

1. Aucubin ameliorates liver fibrosis and hepatic stellate cells activation in diabetic mice via inhibiting ER stress-mediated IRE1alpha/TXNIP/NLRP3 inflammasome through NOX4/ROS pathway;Bao;Chem. Biol. Interact.,2022

2. Ischaemic stroke;Campbell;Nat. Rev. Dis. Primers,2019

3. Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats;Chen;Stroke.,2001

4. KEAP1-NRF2 protein-protein interaction inhibitors: design, pharmacological properties and therapeutic potential;Crisman;Med. Res. Rev.,2023

5. Aucubin ameliorates the LPS-induced inflammatory response in bovine endometrial epithelial cells by inhibiting NF-kappaB and activating the Keap1/Nrf2 signalling pathway;Gao;Reprod. Domest. Anim.,2021

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