Long-term mildronate treatment increased Proteobacteria level in gut microbiome, and caused behavioral deviations and transcriptome change in liver, heart and brain of healthy mice
Author:
Funder
RFBR
scientific school
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference64 articles.
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1. Protection of Testis against Lipopolysaccharide-Induced Toxicity: Mildronate-Induced L-Carnitine Depletion as a Modulator of Gut Microbiome Composition and Gastrointestinal Inflammation;Gastrointestinal Disorders;2023-12-05
2. Age-Related Decline in Nrf2/ARE Signaling Is Associated with the Mitochondrial DNA Damage and Cognitive Impairments;International Journal of Molecular Sciences;2022-12-02
3. Effect of l-carnitine and mildronate on the mitochondrial metabolism of heart and bacterial composition of the gut microbiome in ageing mice;Life Sciences;2022-03
4. Mildronate protects heart mtDNA from oxidative stress toxicity induced by exhaustive physical exercise;Archives of Biochemistry and Biophysics;2021-07
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