Re-positioning of low dose paclitaxel against depressive-like behavior and neuroinflammation induced by lipopolysaccharide in rats: Crosstalk between NLRP3/caspase-1/IL-1β and Sphk1/S1P/ NF-κB signaling pathways

Author:

Elzaitony Asmaa S.,Al-Najjar Aya H.,Gomaa Asmaa A.,Eraque Ayat M.S.,Sallam Amany Said

Publisher

Elsevier BV

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1. Galangin mitigates DOX-induced cognitive impairment in rats: implication of NOX-1/Nrf-2/HMGB1/TLR4 and TNF-α/MAPKs/RIPK/MLKL/BDNF;Abd El-Aal;Neurotoxicology,2022

2. Pramipexole and lactoferrin ameliorate cyclophosphamide-induced haemorrhagic cystitis via targeting Sphk1/S1P/MAPK, TLR-4/NF-κB, and NLRP3/caspase-1/IL-1β signalling pathways and modulating the Nrf2/HO-1 pathway;Abdel Baky;Int. Immunopharmacol.,2022

3. Fluoxetine ameliorates Alzheimer’s disease progression and prevents the exacerbation of cardiovascular dysfunction of socially isolated depressed rats through activation of Nrf2/HO-1 and hindering TLR4/NLRP3 inflammasome signaling pathway;Abu-Elfotuh;Int. Immunopharmacol.,2022

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5. Forced Swimming-Induced Depressive-like Behavior and Anxiety Are Reduced by Chlorpheniramine via Suppression of Oxidative and Inflammatory Mediators and Activating the Nrf2-BDNF Signaling Pathway;Alamri,2023

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