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Mechanism of chloroform-induced renal toxicity: Non-involvement of hepatic cytochrome P450-dependent metabolism

  • Published:2008-02 Issue:1 Volume:227 Page:48-55
  • ISSN:0041-008X
  • Container-title:Toxicology and Applied Pharmacology
  • language:en
  • Short-container-title:Toxicology and Applied Pharmacology

Author:

Fang Cheng,Behr Melissa,Xie Fang,Lu Shijun,Doret Meghan,Luo Hongxiu,Yang Weizhu,Aldous Kenneth,Ding Xinxin,Gu Jun

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference34 articles.

1. Adaptive tolerance in mice upon subchronic exposure to chloroform: increased exhalation and target tissue regeneration;Anand;Toxicol. Appl. Pharmacol.,2006

2. Glutathione-dependent toxicity;Anders;Xenobiotica,1992

3. Renal xenobiotic metabolism: role in bioactivation of nephrotoxic xenobiotics;Anders,1993

4. Nephrotoxicity of chloroform: metabolism to phosgene by the mouse kidney;Branchflower;Toxicol. Appl. Pharmacol.,1984

5. P450-cytochromes: structure and function;Black;Adv. Enzymol. Relat. Areas Mol. Biol.,1987

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