The role of renal proximal tubule P450 enzymes in chloroform-induced nephrotoxicity: Utility of renal specific P450 reductase knockout mouse models

Author:

Liu Senyan,Yao Yunyi,Lu Shijun,Aldous Kenneth,Ding Xinxin,Mei Changlin,Gu Jun

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference29 articles.

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3. Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice;Constan;Toxicol. Appl. Pharmacol.,1999

4. Cellular distribution of cytochromes P-450 in the rat kidney;Cummings;Drug Metab. Dispos.,1999

5. Expression of glutathione-dependent enzymes and cytochrome P450s in freshly isolated and primary cultures of proximal tubular cells from human kidney;Cummings;J. Pharmacol. Exp. Ther.,2000

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