Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma
Author:
Publisher
Elsevier BV
Subject
General Biochemistry, Genetics and Molecular Biology
Reference57 articles.
1. A new prognostic score supporting treatment allocation for multimodality therapy for malignant pleural mesothelioma: a review of 12 Years' experience;Opitz;J. Thorac. Oncol.,2015
2. First-line nivolumab plus ipilimumab in unresectable malignant pleural mesothelioma (CheckMate 743): a multicentre, randomised, open-label, phase 3 trial;Baas;Lancet,2021
3. The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma;Bott;Nat. Genet.,2011
4. Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations;Bueno;Nat. Genet.,2016
5. BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITs;Carbone;J. Transl. Med.,2012
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1. Leukocyte immunoglobulin-like receptor B1 (LILRB1) protects human multiple myeloma cells from ferroptosis by maintaining cholesterol homeostasis;Nature Communications;2024-07-09
2. Saturation genome editing of BAP1 functionally classifies somatic and germline variants;Nature Genetics;2024-07
3. Loss of RNF2 delays tumour development in BAP1-deficient mesothelioma;2024-04-27
4. Combination of EZH2 and ATM inhibition in BAP1-deficient mesothelioma;British Journal of Cancer;2024-03-22
5. Dual targeting of EZH2 and Histone Deacetylases in hematological malignancies promotes transcriptional and metabolic deregulation leading to ferroptosis;2024-03-08
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