Hypoxia-inducible factor 1α activates the NLRP3 inflammasome to regulate epithelial differentiation in chronic rhinosinusitis

Author:

Zhong Bing,Sun Silu,Tan Kai Sen,Ong Hsiao Hui,Du Jintao,Liu Feng,Liu Yafeng,Liu Shixi,Ba Luo,Li JingORCID,Wang De Yun,Liu Jing

Funder

Sichuan Province Science and Technology Support Program

National Medical Research Council

China Postdoctoral Science Foundation

Sichuan University

Sichuan University West China Hospital

Natural Science Foundation of Sichuan Province

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference49 articles.

1. P-glycoprotein inhibition with verapamil overcomes mometasone resistance in chronic sinusitis with nasal polyps;Taha;Rhinology,2021

2. P-glycoprotein promotes epithelial T helper 2–associated cytokine secretion in chronic sinusitis with nasal polyps;Bleier;Int Forum Allergy Rhinol,2014

3. Extrafollicular PD-1highCXCR5−CD4+ T cells participate in local immunoglobulin production in nasal polyps;Wang;J Allergy Clin Immunol,2022

4. Mechanisms and pathogenesis of chronic rhinosinusitis;Kato;J Allergy Clin Immunol,2022

5. Increased noneosinophilic nasal polyps in chronic rhinosinusitis in US second-generation Asians suggest genetic regulation of eosinophilia;Mahdavinia;J Allergy Clin Immunol,2015

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