Naturally-existing CD4+CD25+Foxp3+ regulatory T cells are required for tolerance to experimental autoimmune thyroiditis induced by either exogenous or endogenous autoantigen

Author:

Morris Gerald P.,Brown Nicholas K.,Kong Yi-chi M.

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference55 articles.

1. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J Immunol,1995

2. Administration of anti-interleukin-2 receptor α antibody in vivo induces localized autoimmune disease;Taguchi;Eur J Immunol,1996

3. Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease;McHugh;J Immunol,2002

4. H2A- and H2E-derived CD4+CD25+ regulatory T cells: a potential role in reciprocal inhibition by class II genes in autoimmune thyroiditis;Morris;J Immunol,2005

5. Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells;Mottet;J Immunol,2003

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