Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue

Author:

Rysnik OliwiaORCID,McHugh Kirsty,van Duivenvoorde Leonie,van Tok Melissa,Guggino Giuliana,Taurog Joel,Kollnberger Simon,Ciccia Francesco,Baeten Dominique,Bowness Paul

Funder

Massachusetts Institute of Technology

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference46 articles.

1. Cutting edge: HLA-B27 can form a novel beta 2-microglobulin-free heavy chain homodimer structure;Allen;J. Immunol.,1999

2. HLA-B27 misfolding and ankylosing spondylitis;Colbert;Mol. Immunol.,2014

3. HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors;Kollnberger;J. Immunol.,2004

4. Consistent patterns of expression of HLA class I free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological and pathological roles;Raine;Rheumatology,2006

5. Inhibiting HLA – B27 homodimer – driven immune cell inflammation in spondylarthritis;Payeli,2012

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