The role of higher-order protein structure in supporting binding by heteroclitic monoclonal antibodies: The monoclonal antibody KIM185 to CD18 also binds C4-binding protein

Author:

Gjelstrup Louise Carstensen,Andersen Stig Henrik,Petersen Steen Vang,Enghild Jan J.,Blom Anna M.,Vorup-Jensen Thomas,Thiel Steffen

Funder

Sundhed og Sygdom, Det Frie Forskningsråd

Publisher

Elsevier BV

Subject

Molecular Biology,Immunology

Reference57 articles.

1. KIM185, a monoclonal antibody to CD18 which induces a change in the conformation of CD18 and promotes both LFA-1- and CR3-dependent adhesion;Andrew;Eur. J. Immunol.,1993

2. Integrin structure, allostery, and bidirectional signaling;Arnaout;Annu. Rev. Cell Dev. Biol.,2005

3. Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation;Beglova;Nat. Struct. Biol.,2002

4. Dual binding specificities in MOPC 384 and 870 murine myeloma immunoglobulins;Bhattacharjee;J. Immunol.,1978

5. Structural and functional studies of complement inhibitor C4b-binding protein;Blom;Biochem. Soc. Trans.,2002

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