Critical comparison of shake-flask, potentiometric and chromatographic methods for lipophilicity evaluation (log P o/w ) of neutral, acidic, basic, amphoteric, and zwitterionic drugs-Reference-Cited by-同舟云学术

Critical comparison of shake-flask, potentiometric and chromatographic methods for lipophilicity evaluation (log P o/w ) of neutral, acidic, basic, amphoteric, and zwitterionic drugs

Published:2018-09 Issue: Volume:122 Page:331-340
ISSN:0928-0987
Container-title:European Journal of Pharmaceutical Sciences
language:en
Short-container-title:European Journal of Pharmaceutical Sciences

Author:

Port Adriana,Bordas Magda,Enrech Raquel,Pascual Rosalia,Rosés Martí^ORCID,Ràfols Clara^ORCID,Subirats Xavier^ORCID,Bosch Elisabeth^ORCID

Funder

Ministry of Science, Innovation and Universities of Spain

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference45 articles.

1. Scales of solute hydrogen-bonding: their construction and application to physicochemical and biochemical processes;Abraham;Chem. Soc. Rev.,1993

2. Setup and validation of shake-flask procedures for the determination of partition coefficients (log D) from low drug amounts;Andrés;Eur. J. Pharm. Sci.,2015

3. Photostability and phototoxicity studies on diltiazem;Andrisano;J. Pharm. Biomed. Anal.,2001

4. The influence of lipophilicity in drug discovery and design;Arnott;Expert Opin. Drug Discovery,2012

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Critical Assessment of pH‐Dependent Lipophilicity Profiles of Small Molecules: Which One Should We Use and In Which Cases?;ChemPhysChem;2023-10-24

2. Physicochemical Properties of Drugs for Use in the Pharmaceutical Industry;Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays;2023

3. Physicochemical property determinations by liquid chromatography;Liquid Chromatography;2023

4. Towards an Understanding of the Lipophilicity of Non-Coded Amino Acids: Computational Simulations of Proline Analogs;2022 IEEE 4th International Conference on BioInspired Processing (BIP);2022-11-15

5. Fast Prediction of Lipophilicity of Organofluorine Molecules: Deep Learning-Derived Polarity Characters and Experimental Tests;Journal of Chemical Information and Modeling;2022-10-12