Activation of benzoate model prodrugs by mycobacteria. Comparison with mammalian plasma and liver hydrolysis

Author:

Valente Emília,Testa Bernard,Constantino LuísORCID

Funder

Fundacao para a Ciencia e a Tecnologia

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference28 articles.

1. Batt, S.M., Minnikin, D.E., Besra, G.S., 2020. The thick waxy coat of mycobacteria, a protective layer against antibiotics and the host's immune system. https://doi.org/10.1042/BCJ20200194.

2. Quantitative structure-activity relationships for the in vitro antimycobacterial activity of pyrazinoic acid esters;Bergmann;J. Med. Chem.,1996

3. Physicochemical aspects of the enzymatic hydrolysis of carboxylic esters;Buchwald;Pharmazie,2002

4. Bundgaard, H., 1992. A Textbook of Drug Design and Development, in: Krogsgaard-Larsen P., B.H. (Ed.), Harwood Academic Publishers, Switzerland, pp. 153–160.

5. Camus, J.-C., Pryor, M.J., Me, C., Cole, S.T., 2002. Re-annotation of the genome sequence of mycobacterium tuberculosis H37Rv, microbiology.

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