Enhanced P-glycoprotein expression under high-altitude hypoxia contributes to increased phenytoin levels and reduced clearance in rats
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference21 articles.
1. Identification and quantification of blood-brain barrier transporters in isolated rat brain microvessels;Al Feteisi;J. Neurochem,2018
2. Blood-brain barrier (BBB) and the complement landscape;Alexander;Mol. Immunol,2018
3. Asiatic acid (AA) sensitizes multidrug-resistant human lung adenocarcinoma A549/DDP cells to cisplatin (DDP) via downregulation of P-glycoprotein (MDR1) and its targets;Cheng;Cell. Physiol. Biochem.,2018
4. Potential role of ABC transporters as a detoxification system at the blood-CSF barrier;de Lange;Adv. Drug. Deliv. Rev.,2004
5. Pluronic P85-coated poly(butylcyanoacrylate) nanoparticles overcome phenytoin resistance in P-glycoprotein overexpressing rats with lithium-pilocarpine-induced chronic temporal lobe epilepsy;Fang;Biomaterials,2016
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