Development and validation of a LC-HRMS method for the quantification of cannabinoids and their metabolites in human plasma

Author:

Mohamed Mahmoud KamelORCID,Takyi-Williams JohnORCID,Baudot Bertrand,Grobler AnneORCID

Funder

North-West University

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference28 articles.

1. Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential (Book);Zuardi;Choice Curr. Rev. Acad. Lib.40,2003

2. Identification and quantification of cannabinoids in Cannabis sativa L. plants by high performance liquid chromatography-mass spectrometry;Aizpurua-Olaizola;Anal. Bioanal. Chem.,2014

3. Improving LC–MS sensitivity through increases in chromatographic performance: Comparisons of UPLC–ES/MS/MS to HPLC–ES/MS/MS;Churchwell;J. Chroma. B,2005

4. Simultaneous quantification of Δ9-tetrahydrocannabinol, 11-nor-9-carboxy-tetrahydrocannabinol, cannabidiol and cannabinol in oral fluid by microflow-liquid chromatography-high resolution mass spectrometry;Concheiro;J. Chroma. A,2013

5. Guideline on Bioanalytical Method Validation;European Medicines Agency,2011

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