Comparative QM/MM study on the inhibition mechanism of β-Hydroxynorvaline to Threonyl-tRNA synthetase

Author:

Aboelnga Mohamed M.ORCID,Gauld James W.

Funder

Natural Sciences and Engineering Research Council of Canada

Compute Canada

Publisher

Elsevier BV

Subject

Materials Chemistry,Computer Graphics and Computer-Aided Design,Physical and Theoretical Chemistry,Spectroscopy

Reference59 articles.

1. Inhibitors of aminoacyl-tRNA synthetases as novel anti-infectives;Tao;Expet Opin. Invest. Drugs,2000

2. Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents;Ochsner;Expet Opin. Invest. Drugs,2007

3. Aminoacyl-tRNA synthetases and their inhibitors as a novel family of antibiotics;Kim;Appl. Microbiol. Biotechnol.,2003

4. Nature 347: 249-255;Cusack;Nature 1990,1990

5. Cellular mechanisms that control mistranslation;Reynolds;Nat. Rev. Microbiol.,2010

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