Molecular mechanism of D816X mutation-induced c-Kit activation and -mediated inhibitor resistance in gastrointestinal stromal tumor-Reference-Cited by-同舟云学术

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Molecular mechanism of D816X mutation-induced c-Kit activation and -mediated inhibitor resistance in gastrointestinal stromal tumor

Published:2018-09 Issue: Volume:84 Page:189-196
ISSN:1093-3263
Container-title:Journal of Molecular Graphics and Modelling
language:en
Short-container-title:Journal of Molecular Graphics and Modelling

Author:

Jiang Haohai,Shao Weiwei,Wang Yuanjin,Xu Ronghui,Zhou Linsen,Mu Xiangming

Funder

Yancheng Medical Science and Technology Development Project

Publisher

Elsevier BV

Subject

Materials Chemistry,Computer Graphics and Computer-Aided Design,Physical and Theoretical Chemistry,Spectroscopy

Reference53 articles.

1. Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes;Andre;Genomics,1997

2. c-Kit protein, a transmembrane kinase: identification in tissues and characterization;Majumder;Mol. Cell Biol.,1988

3. KIT oncogenic mutations: biologic insights, therapeutic advances, and future directions;Fletcher;Canc. Res.,2016

4. Classes of c-KIT activating mutations: proposed mechanisms of action and implications for disease classification and therapy;Longley;Leuk. Res.,2001

5. Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-Kit product;Furitsu;J. Clin. Invest.,1993

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Developing and Characterization of Chemically Modified RNA Aptamers for Targeting Wild Type and Mutated c-KIT Receptor Tyrosine Kinases;Journal of Medicinal Chemistry;2019-08-01

2. Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants;Journal of Medicinal Chemistry;2019-04-10

3. Electrostatic explanation of D1228V/H/N-induced c-Met resistance and sensitivity to type I and type II kinase inhibitors in targeted gastric cancer therapy;Journal of Molecular Modeling;2019-01

4. Electrostatic mechanism of V600E mutation-induced B-Raf constitutive activation in colorectal cancer: molecular implications for the selectivity difference between type-I and type-II inhibitors;European Biophysics Journal;2018-09-14

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