A potential effect of ganaxolone in an animal model of infantile spasms

Author:

Yum Mi-Sun,Lee Minyoung,Ko Tae-Sung,Velíšek Libor

Funder

Korean Health Industry Development Institute

Korean Child Neurology Society

Publisher

Elsevier BV

Subject

Neurology (clinical),Neurology

Reference27 articles.

1. Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor;Carter;J. Pharmacol. Exp. Ther.,1997

2. Neurosteroid interactions with synaptic and extrasynaptic GABAA receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability;Carver;Psychopharmacology (Berl.),2013

3. Validation of the rat model of cryptogenic infantile spasms;Chachua;Epilepsia,2011

4. Dexamethasone rapidly increases GABA release in the dorsal motor nucleus of the vagus via retrograde messenger-mediated enhancement of TRPV1 activity;Derbenev;PLoS ONE,2013

5. Protracted developmental trajectories of GABAA receptor alpha1 and alpha2 subunit expression in primate prefrontal cortex;Hashimoto;Biol. Psychiatry,2009

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