Comet assay studies on the activation of two diaziridinylbenzoquinones in K562 cells

Author:

Ward Timothy H.,Butter John,Shahbakhti Hassan,Richards John T.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference25 articles.

1. Diaziquone;Bender;Invest New Drugs,1983

2. Treatment of patients with recurrent primary brain tumours with AZQ;Schold;Neurology,1984

3. Contrasting cytotoxic mechanisms of similar antitumour diaziridinylbenzoquinones;Butler;Free Rad Res Comms,1990

4. Mechanisms of DNA strand breakage and interstrand cross-linking by diaziridinylbenzoquinone (Diaziquone) in isolated nuclei from human cells;Szmigiero;Cancer Res,1984

5. Reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells. II. Enhancement of the alkylating activity of AZQ by NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase);Fisher;Biochem Pharmacol,1993

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