Strain Differences in CYP3A-Mediated C-8 Hydroxylation (1,3,7-Trimethyluric Acid Formation) of Caffeine in Wistar and Dark Agouti Rats

Author:

Morita Keiichi,Maeda Yutaka,Masuda Makihiko,Kazusaka Akio,Imaoka Susumu,Funae Yoshihiko,Fujita Shoichi

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference32 articles.

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2. Biotransformation of caffeine paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome(s) P-450 in human liver microsomes;Campbell;Drug Metab Dispos,1987

3. Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies;Grant;Biochem Pharmacol,1987

4. Ribon B, Benchekroun Y, Desage M, Riou JP and Brazier JL, Metabolism of caffeine and three of its tri-deuteromethyl isotopomers. In: Liver Cells and Drugs (Ed. Guillouzo A), Vol. 164, pp. 269–274. Colloque INSERM, John Libbey Eurotext Ltd., Paris, 1988.

5. Berthou F, Ratanasavanh D, Riche C and Guillouzo A, Caffeine metabolism by human and rat hepatocytes in primary culture. In: Liver Cells and Drugs (Ed. Guillouzo A), Vol. 164, pp. 287–292. Colloque INSERM, John Libbey Eurotext Ltd., Paris, 1988.

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