CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6α-hydroxylase activity in human liver microsomes

Author:

Bahadur Namrata,Leathart Julian B.S,Mutch Elaine,Steimel-Crespi Dorothy,Dunn Stuart A,Gilissen Ron,Houdt Jos Van,Hendrickx Jan,Mannens Geert,Bohets Hilde,Williams Faith M,Armstrong Martin,Crespi Charles L,Daly Ann K

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference45 articles.

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2. Selective biotransformation of taxol to 6-alpha-hydroxytaxol by human cytochrome-P450 2C8;Rahman;Cancer Res.,1994

3. Identification of human cytochrome P450 isoforms that contribute to all-trans-retinoic acid 4-hydroxylation;McSorley;Biochem. Pharmacol.,2000

4. Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans;Busse;Naunyn Schmiedebergs Arch. Pharmacol.,1995

5. Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-4502C8 and P-450 3A4 in human liver microsomes;Yamazaki;Drug Metab. Dispos.,1999

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