Selective inhibition of bacterial dihydroorotate dehydrogenases by thiadiazolidinediones

Author:

Marcinkeviciene Jovita,Rogers M.John,Kopcho Lisa,Jiang Wenjun,Wang Kathy,Murphy Dennis J,Lippy Jonathan,Link Steven,Chung Thomas D.Y,Hobbs Frank,Haque Tasir,Trainor George L,Slee Andrew,Stern Andrew M,Copeland Robert A

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference15 articles.

1. Generation of auxotrophic mutants of Enterococcus faecalis;Li;J Bacteriol,1995

2. Evolutionary and functional families of dihydroorotate dehydrogenases;Jensen;Paths Pyrimidines,1998

3. Mechanism of action of the novel anticancer agent 6-fluoro-2-(2′-fluoro-1,1′-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium salt (NSC 368390);Chen;Cancer Res,1986

4. Leflunomide inhibits pyrimidine de novo synthesis in mitogen-stimulated T-lymphocytes from healthy humans;Ruckermann;J Biol Chem,1998

5. Inhibition of dihydroorotate dehydrogenase activity by brequinar sodium;Chen;Cancer Res,1992

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