Does the antitumor cyclopropylpyrroloindole antibiotic CC-1065 cross-link DNA in tumor cells?

Author:

Skladanowski Andrzej,Koba Marcin,Konopa Jerzy

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference26 articles.

1. CC-1065 (NSC-298223), a new antitumor antibiotic. Production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganism;Hanka;J Antibiot (Tokyo),1978

2. Covalent binding of antitumor antibiotic in the minor groove of DNA. Mechanism of action of CC-1065 and the pyrrolo(1,4)benzoadepines;Hurley;Acc Chem Res,1986

3. CC-1065;Remers,1988

4. Structure and activity relationship of several novel CC-1065 analogs;Li;Invest New Drugs,1987

5. DNA interstrand cross-linking, DNA sequence specificity, and induced conformational changes produced by a dimeric analog of (+)-CC-1065;Ding;Anticancer Drug Des,1991

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