Anti-anxiety effects of progesterone and some of its reduced metabolites: an evaluation using the burying behavior test

Author:

Picazo O.,Ferna´ndez-Guasti A.

Publisher

Elsevier BV

Subject

Developmental Biology,Neurology (clinical),Molecular Biology,General Neuroscience

Reference49 articles.

1. Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor;Bitran;Brain Res.,1991

2. Blockade of the bio-conversion of progesterone to allopregnanolone prevents the anxiolytic effect and potentiation of cortical GABAA receptor function observed in progesterone-treated ovariectomized rats;Bitran;Soc. Neurosc. Abstr.,1993

3. Anxiolytic effect of progesterone is associated with increases in cortical allopregnanolone and GABAA receptor function;Bitran;Pharmacol. Biochem. Behav.,1993

4. Biochemical and behavioral effects of steroids on GABAA receptor function in long- and short-sleep mice;Bowers;Brain Res. Bull.,1992

5. Modulation of the GABAA receptor by progesterone metabolites;Callachan,1987

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