Optimization of conditions for conversion of tylosin to a novel antibiotic, acetyl-isovaleryl tylosin (AIV), by Streptomyces thermotolerans and scale-up to 200-liter pilot-scale fermentor-Reference-Cited by-同舟云学术

Optimization of conditions for conversion of tylosin to a novel antibiotic, acetyl-isovaleryl tylosin (AIV), by Streptomyces thermotolerans and scale-up to 200-liter pilot-scale fermentor

Published:1997-01 Issue:1 Volume:84 Page:77-81
ISSN:0922-338X
Container-title:Journal of Fermentation and Bioengineering
language:en
Short-container-title:Journal of Fermentation and Bioengineering

Author:

Huang Guowei,Okamoto Rokuro,Hikita Atsushi,Park Yongsoo,Okabe Mitsuyasu

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,Biotechnology

Reference7 articles.

1. The activity of 4″-acylated tylosin derivatives against macrolide-resistant gram-positive bacteria;Okamoto;J. Antibiot.,1979

2. Screening for 16-membered macrolide-transforming microorganisms;Okamoto;J. Ferment. Bioeng.,1979

3. Novel acyl derivatives of tylosin produced by microbial transformation;Okabe,1993

4. Cloning and nucleotide sequences of two genes involved in the 4″-O-acylation of macrolide antibiotics from Streptomyces thermotolerans;Arisawa;Biosci. Biotech. Biochem.,1993

5. Cloning of the macrolide antibiotic biosynthesis gene acy A, which encodes 3-O-acyltransferase, from Streptomyces thermotolerans and its use for direct fermentative production of a hybrid macrolide antibiotic;Arisawa;Appl. Environ. Microbiol.,1994

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