Synthesis, hydroxyl radical production and cytotoxicity of analogues of bleomycin-Reference-Cited by-同舟云学术

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Synthesis, hydroxyl radical production and cytotoxicity of analogues of bleomycin

Published:2000-05 Issue:5 Volume:8 Page:1065-1073
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Highfield Jackie A.,Mehta Lina K.,Parrick John,Wardman Peter

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. Synthesis and properties of prodrugs activated in hypoxia to give bleomycin analogues

2. Highfield, J. A.; Mehta, L. K.; Parrick, J.; Candeias, L. P.; Wardman, P. J. Chem. Soc., Perkin Trans 1 1999, 2343

3. On the role of the bithiazole moiety in sequence-selective DNA cleavage by Fe.bleomycin.

4. (a) Kross, J.; Henner, W. D.; Heseltine, W. A.; Rodriguez, L.; Levin, W. D.; Hecht, S. M. Biochemisry 1982, 21, 3711. (b) Fisher, L. M.; Kuroda, R.; Sakai, T. T. Biochemistry 1985, 24, 3199. (c) Kennani, A.; Lohez, M.; Houssin, R.; Helbecque, N.; Bernier, J. L.; Lemay, P.; Henichart, J. P. Anti-Cancer Drug Design 1987, 2, 47. (d) Vloon, W. J.; Kruk, C.; Pandit, U. K.; Hofs, H. P.; McVie, J. G. J. Med. Chem. 1987, 30, 20. (e) Carter, B. J.; Murty, V. S.; Reddy, K. S.; Wang, S.-N.; Hecht, S. M. J. Biol. Chem. 1990, 265, 4193. (f) Boger, D. L.; Colletti, S. L.; Honda, T.; Menezes, R. F. J. Am. Chem. Soc. 1994, 116, 5607.

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