Targeting RAS oncogenesis with SOS1 inhibitors
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Elsevier
Reference85 articles.
1. Discovery of aminopiperidine indoles that activate the guanine nucleotide exchange factor SOS1 and modulate RAS signaling;Abbott;Journal of Medicinal Chemistry,2018
2. Discovery of quinazolines that activate SOS1-mediated nucleotide exchange on RAS;Abbott;ACS Medicinal Chemistry Letters,2018
3. Small molecule SOS1 agonists modulate MAPK and PI3K signaling via independent cellular responses;Akan;ACS Chemical Biology,2019
4. Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival;Baltanas;Molecular and Cellular Biology,2013
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